Diphenylurea compounds

A compound selected from those of formula (I):

• wherein
• R1, R2, R3 and R4 independently represent hydrogen, halogen or alkyl, alkoxy, hydroxy, alkylthio, mercapto, cyano, amino (optionally substituted by one or two alkyl), nitro, carboxy, alkoxycarbonyl, aminocarbonyl (optionally substituted by one or two alkyl) or carbamoyl,
• or, taken in pairs, form together with the carbon atoms to which they are bonded a phenyl ring,
• L1 and L2 each represents hydrogen or together form —CH2—CH2—,
• X1, attached at the 2 or 3 position of the aromatic ring, represents a bond, and in that case X2 represents hydrogen, halogen, alkyl, alkoxy, hydroxy, nitro or cyano, or amino (optionally substituted by one or two alkyl),
• or, X1 and X2, together with two adjacent carbons to which they are bonded in the 2, 3 or 4 position of the aromatic ring, form (C4-C7)cycloalkyl wherein one carbon of the cycloalkyl ring is substituted by G,
• X3 represents hydrogen, halogen, alkyl, alkoxy, hydroxy, nitro or cyano, or amino (optionally substituted by one or two alkyl),
• G represents
• wherein:
• T3 represents optionally substituted heteroaryl or optionally substituted heteroarylalkyl,
• wherein:
• the term “alkyl” denotes linear or branched group having from 1 to 6 carbon,
• the term “alkoxy” denotes linear or branched alkyl-oxy having from 1 to 6 carbon,
• the term “heteroaryl” denotes a benzodioxinyl group,
• the expression “optionally substituted” associated with heteroaryl and heteroarylalkyl denotes that those groups are unsubstituted or substituted on the cyclic moiety by one or more halogen and/or alkyl, alkoxy, hydroxy, mercapto, alkylthio, cyano, amino (optionally substituted by one or two alkyl), nitro, carboxy, alkoxycarbonyl, aminocarbonyl (optionally substituted by one or two alkyl) or carbamoyl, wherein heteroaryl and heteroarylalkyl may in addition be substituted by oxo, its enantiomers and diastereoisomers thereof, and addition salts thereof with a pharmaceutically acceptable acid or base.