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US 6,783,955 B2Granted
Polynucleotides encoding human presenilin variant
AssigneeIncyte Corporation
InventorsChandra Arvizu, Lynn E. Murry, Matthew R. Kaser
Life of this patent
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Abstract
The invention provides a cDNA which encodes human presenilin variant. It also provides for the use of the cDNA and protein in the diagnosis, prognosis, treatment and evaluation of therapies for cancer or neurodegenerative or immune disorders. The invention further provides vectors and host cells for the production of the protein and transgenic model systems.
Claims12
An isolated cDNA, or the complement thereof, comprising a nucleic acid sequence encoding a protein having and amino acid sequence of SEQ ID NO:1.
An isolated cDNA comprising a nucleic acid sequence selected from:
- a) SEQ ID NO:2 or the complement thereof
- b) SEQ ID NO:5, or the complement thereof, and
- c) SEQ ID NO:6 or the complement thereof.
Dependencies are inferred from the claim text.