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US 6,783,944 B2Granted
Genetic changes in atypical nodular proliferations in congenital melanocytic nevi
AssigneeThe Regents of the University of California
InventorBoris C. Bastian
Life of this patent
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Abstract
The invention provides methods of distinguishing benign growths arising from congenital melanocytic nevi from malignant melanoma. The methods comprise detecting a change in chromosome number that is specifically associated with benign growths. These changes include a gain of chromosome 10, a gain of chromosome 11, and a loss of chromosome 7.
Claims15
A method of typing a proliferative nodule in a congenital melanocytic nevus as a benign growth, the method comprising providing a nucleic acid sample from the nodule and detecting a loss of whole chromosome 7 thereby typing the nodule as a benign growth.
Dependencies are inferred from the claim text.