Isolated polynucleotide associated with type II diabetes mellitus and methods of use thereof
AssigneeThe UAB Research Foundation
InventorSusan M. Sell
Life of this patent
Estimating the term…
Abstract
The present invention provides isolated polynucleotides that include sequences from a region of human chromosome 20q between D20S119 and D20S195. The polynucleotides include polymorphisms associated with Type II diabetes and are useful as probes in screening for Type II diabetes. The invention further provides vectors and isolated host cells comprising the isolated polynucleotides. The invention further provides methods of detecting polymorphisms on chromosome 20q between D20S119 and D20S195, and methods of detecting a propensity to develop Type II diabetes, using the isolated polynucleotides of the invention.
Claims5
A method for detecting a predisposition of an individual to develop Type II diabetes, comprising analyzing a polynucleotide sample derived from the individual for the presence of a nucleotide sequence of SEQ ID NO:7, wherein the presence of a nucleotide sequence of SEQ ID NO:7 is indicative of a predisposition in the individual to develop Type II diabetes.
Dependencies are inferred from the claim text.