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US 6,783,930 B1Granted
Development of novel anti-microbial agents based on bacteriophage genomics
OwnerJerry Pelletier, Philippe Gros +1inventors
InventorsJerry Pelletier, Philippe Gros, Michael DuBow
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Abstract
A method for identifying suitable targets for antibacterial agents based on identifying targets of bacteriophage-encoded proteins is described. Also described are compositions useful in the identification methods and in inhibiting bacterial growth, and methods for preparing and using such compositions.
Claims10
A method for identifying at least one target for antibacterial agents, comprising
- contacting a bacterial protein with a bacterial growth inhibitory bacteriophage polypeptide;
- determining whether said bacterial growth inhibitory bacteriophage polypeptide binds to said bacterial protein;
- and
- identifying any said bacterial protein bound by said bacterial growth inhibitory bacteriophage polypeptide wherein binding of said bacterial growth inhibitory bacteriophage polypeptide to said bacterial protein is indicative that said bacterial protein is a said target.
1 more element
Dependencies are inferred from the claim text.