US 6,783,759 B2Granted

Compositions and methods for modulating variola virus

AssigneeThe Trustees of the University of Pennsylvania

InventorAriella M. Rosengard

Life of this patent

Estimating the term…

Abstract

Antibodies directed to SPICE which may be used for detection, prevention, and treatment of variola virus are provided. Recombinant SPICE and VCP proteins are also provided which are used for enhancing the immune response to variola virus. Furthermore, modulation of complement activation by administering recombinant SPICE and VCP is provided.

Claims6

Dependent claims

An isolated monoclonal antibody which specifically binds SPICE and VCP.

Dependencies are inferred from the claim text.

Facts

Application: 10/108,311Filed 27 Mar 2002
Published: US 2004/0038196 A126 Feb 2004
Granted: 31 Aug 2004
Term ends: Not estimatedThe source records don’t support an estimate.

Classification16 codes

C07K 14/005
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof: from viruses
C07H 21/04
Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of…: with…
C07K 16/081
Against material from viruses: dNA viruses
C12Q 1/70
Measuring or testing processes involving enzymes, nucleic acids or microorganisms ; Compositions therefor; Processes of preparing such…

Family

US 2004/0038196 A1Pre-grant publication · published 26 Feb 2004
US 6,783,759 B2This patent

From the US filing history. Foreign family members aren’t listed.

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