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AssigneeBristol-Myers Squibb Company
InventorsJoseph Nolfo, Maxine Soumellant, Victor W. Rosso, Peter Lee, Mayra B. Reyes, John J. Venit
Estimating the term…
Multiple parallel chemical reactions are performed under pressure in a reactor including a multi-row array of reaction vessels situated between a temperature control base and a fluid flow manifold. The manifold consists of an input portion connected to the fluid supply by a five-way valve and a distribution portion which includes separate parallel distribution channels, one for each row of reaction vessels. A control valve for each distribution channel is interposed between the manifold portions such that the fluid flow to each row of reaction vessels can be independently controlled. An explosion proof transparent shield can be situated between the base and manifold, surrounding the reaction vessels. The interior of the shield can be flooded with inert gas.
Apparatus for performing parallel chemical reactions under pressure, said apparatus comprising first and second sets of reaction vessels, at least one of said vessel sets comprising more than one reaction vessel, a first source of a first fluid, a second source of a second fluid, a fluid manifold, said fluid manifold comprising a source selection portion, a fluid distribution portion and a valve portion interposed between said source selection portion and said fluid distribution portion, said source selection portion comprising means for selecting one of said fluid sources and for connecting said selected source to said valve portion, said fluid distribution portion comprising first and second fluid distribution channels, means for separately connecting each of said fluid distribution channels to each of the reaction vessels in a different one of said reaction vessel sets, respectively, said valve portion comprising first and second valve bodies each of which is associated with a different one of said fluid distribution channels in said fluid distribution portion, and means for independently actuating said valve bodies to connect said source selecting means in said source selection portion and said fluid distribution channel in said fluid distribution portion associated with the actuated valve body.
Apparatus for performing parallel chemical reactions under pressure, said apparatus comprising an array of reaction vessels, said vessel array comprising first and second rows of reaction vessels, at least one of said vessel rows comprising more than one reaction vessel, a first source of a first fluid, a second source of a second fluid, a fluid manifold, said fluid manifold comprising a source selection portion, a fluid distribution portion and a valve portion interposed between said source selection portion and said fluid distribution portion, said source selection portion comprising means for selecting one of said fluid sources and for connecting said selected source to said valve portion, said fluid distribution portion comprising first and second fluid distribution channels, means for separately connecting each of said fluid distribution channels with each of the reaction vessels in a different one of said rows, respectively, said valve portion comprising first and second valve bodies each of which is associated with a different one of said fluid distribution channels in said fluid distribution portion, and means for independently actuating said valve bodies to connect said source selecting means in said source selection portion and said fluid distribution channel in said fluid distribution portion associated with the actuated valve body.
Apparatus for performing parallel chemical reactions under pressure, said apparatus comprising a plurality of sets of reaction vessels, at least one of said vessel sets comprising more than one reaction vessel, a first source of a first fluid, a second source of a second fluid, a fluid manifold, said fluid manifold comprising a first portion, a second portion and an intermediate portion interposed between said first portion and said second portion, said first portion comprising means for selecting one of said fluid sources and for connecting said selected source to said intermediate portion, said second portion comprising a plurality of fluid distribution channels, means for separately connecting each of said fluid distribution channels with each of the reaction vessels in a different one of said reaction vessel sets, respectively, said intermediate portion comprising a plurality of valve bodies, each of said valve bodies being associated with a different one of said fluid distribution channels in said second portion, and means for independently actuating said valve bodies to connect said source selecting means in said first portion and said fluid distribution channel in said second portion associated with the actuated valve body.
Dependencies are inferred from the claim text.