IVC rack system and method for detecting infections particles within an IVC rack system
AssigneeGSF-Forschungszentrum fur Umwelt und Gesundheit GmbH
InventorsJörg Schmidt, Markus Brielmeier
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Abstract
IVC rack system comprising a plurality of IVC cages 13 for test animals which are supplied with sterile air, wherein samples of exhaust air from the IVC cages 13 are supplied from sampling points 15 to at least one sentinel cage 24 housing sentinel animals as bio-indicators for the detection of infectious particles within the exhaust air samples, and to at least one particle sampling filter 33 for the identification of pathogens.
Claims14
An individually ventilated microisolator-cages (IVC) rack system comprising a plurality of IVC cages for housing test animals, means for individually supplying the cages with sterile air, a sentinel cage for housing a sentinel animal, and means for supplying the sentinel cage with exhaust air from the IVC cages, wherein the sentinel animal serves as a bio-indicator for the detection of infectious particles within the exhaust air samples.
Method for detecting infectious particles within an individually ventilated microisolator-cages (IVC) rack system, wherein each IVC cage is provided for housing test animals, the method comprising the following steps:
- (a) filtering of ambient air to generate sterile air;
- (b) supplying the IVC cages of the IVC rack system with the sterile air;
- (c) providing a sentinel cage housing a sentinel animal;
- (d) supplying the sentinel cage with exhaust air from the IVC cages;
- and
- (e) detecting infectious particles within the exhaust air by means of the sentinel animals which act as bio-indicators.
Dependencies are inferred from the claim text.