Libraries of oligomers labeled with different tags

A set of labeled compounds wherein a molecule of a compound of the set is tagged with a single cleavable label which identifies the nature and/or the position of a component of that molecule, wherein each label is cleavable to give a charsed species for mass spectrometry, and different molecules of the same compound are tagged with different labels, wherein each label is a group of formula R1R2R3C—, where R1, R2 and R3 are the same or different and each is a monocyclic or fused ring aromatic group that is substituted or unsubstituted.

A set of labeled compounds wherein a molecule of a compound of the set is tagged with a single cleavable label which identifies the nature and/or the position of a component of that molecule, wherein the label is cleavable to give a charged species for mass spectrometry, and different molecules of the same compound are tagged with different labels, wherein each label is a group of formula R1R2R3C—, where R1, R2 and R3 are the same or different and each is a monocyclic or fused ring aromatic group that is substituted or unsubstituted;

• and
• wherein at least one of R1, R2 and R3 carries a substituent selected from C1-C20 alkoxy or hydrocarbyl either unsubstituted or substituted by carboxylic acid, sulphonic acid, nitro, cyano, hydroxyl, thiol, primary, secondary or tertiary amino, primary or secondary amido, anhydride, carbonyl halide or active ester.

A set of labeled compounds wherein a molecule of a compound of the set is tagged with a single cleavable label which identifies the nature and/or the position of a component of that molecule, wherein the label is cleavable to give a charged species for mass spectrometry, and different molecules of the same compound are tagged with different labels, wherein each label is a group of formula R1R2R3C—, where R1, R2 and R3 are the same or different and each is a monocyclic or fused ring aromatic group that is substituted or unsubstituted and wherein R1R2R3C— is a substituted monomethoxytrityl group.

A library consisting of a set of labeled compounds wherein a molecule of a compound of the set is tagged with a single cleavable label which identifies the nature and/or the position of a component of that molecule, wherein the label is cleavable to give a charged species for mass spectrometry, and different molecules of the same compound are tagged with different labels;

• wherein each label is a group of formula R1R2R3C—, where R1, R2 and R3 are the same or different and each is a monocyclic or fused ring aromatic group that is substituted or unsubstituted.

A library consisting of a set of labeled compounds wherein a molecule of a compound of the set is tagged with a single cleavable label which identifies the nature and/or the position of a component of that molecule, wherein the label is cleavable to give a charged species for mass spectrometry, and different molecules of the same compound are tagged with different labels, wherein each label is a group of formula R1R2R3C—, where R1, R2 and R3 are the same or different and each is a monocyclic or fused ring aromatic group that is substituted or unsubstituted;

• and
• wherein at least one of R1, R2 and R3 carries a substituent selected from C1-C20 alkoxy or hydrocarbyl either unsubstituted or substituted by carboxylic acid, sulphonic acid, nitro, cyano, hydroxyl, thiol, primary, secondary or tertiary amino, primary or secondary amido, anhydride, carbonyl halide or active ester.