Active substance-containing multi-layer film of hydrophilic polymers crosslinked in situ
AssigneeGruenenthal GmbH
InventorsHerbert Rupprecht, Stephan Zinzen
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Abstract
A multi-layered film which contains an active substance and which is made of film-forming polymers. The film comprises at least one covering layer, at least one layer containing the active substance, and an adhesive layer. A method and apparatus for producing such a multi-layered film and a preferred use as a transmucosal galenic formulation are also disclosed.
Claims20
A multi-layer film of film-forming polymers comprising a cover layer, at least one layer containing an active substance, and an adherent layer, wherein the active substance-containing layer comprises hydrophilic polymers crosslinked in situ, and wherein at least one active substance-containing layer has a horizontal and/or vertical gradient as regards the active substance, or the active substance is concentrated in specific horizontal and/or vertical segments of the active substance-containing layer.
Dependencies are inferred from the claim text.