Methods and compositions relating to CD39-like polypeptides and nucleic acids
AssigneeNuvelo, Inc.
InventorsBrian Paul Chadwick, Anna-Maria Frischauf
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Abstract
The present invention provides polynucleotides and proteins encoded by such polynucleotides, along with therapeutic, diagnostic and research utilities for these polynucleotides and proteins. In particular, the polypeptides and polynucleotides of the invention comprise amino acid and nucleic acid sequences of novel CD39-like gene and gene products.
Claims5
An isolated CD39LA polypeptide comprising the amino acid sequence of SEQ ID NO:
- 6 or the mature protein portion thereof.
An isolated polypeptide having phosphohydrolase activity comprising the amino acid sequence of SEQ ID NO:
- 6 or the mature protein portion thereof.
An isolated polypeptide having phosphohydrolase activity comprising an amino acid sequence encoded by a polynucleotide that hybridizes under highly stringent conditions, wherein said conditions are hybridization to a filter-bound DNA in 0.5 M NaHPO4, 7% sodium dodecyl sulfate (SDS), 1 mM EDTA at 65° C., and washing in 0.1×SSC/0.1% SDS at 68° C., to the nucleotide sequence of SEQ ID NO:
- 5 or its complement.
Dependencies are inferred from the claim text.