Methods for producing poly(hydroxy) fatty acids in bacteria
AssigneeMetabolix, Inc.
InventorsAlexander Steinbüchel, Mathias Liebergesell, Henry Valentin, Andreas Pries
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Abstract
The present invention relates to a process for the production of poly (hydroxy fatty acids) as well as recombinant bacterial strains for carrying out the process. In addition, new poly(hydroxy fatty acids) and new substrates for the production of conventional and new poly(hydroxy fatty acids) are described. Moreover, the invention also relates to a DNA fragment, which codes for a PhaE and a PhaC component of the poly(hydroxy fatty acid) synthase from Thiocapsa pfennigii, as well as the corresponding poly (hydroxy fatty acid) synthase protein.
Claims24
A process for the preparation of poly(hydroxy fatty acids) comprising incubating a recombinant bacteria in a mineral medium under aerobic conditions, expressing at least one fragment of the gene encoding the poly(hydroxy fatty acid) synthase from Thiocapsa pfennigii with a substrate carbon source, wherein the recombinant organism produces a poly(hydroxy fatty acid) and, the poly(hydroxy fatty acid) are recovered.
Dependencies are inferred from the claim text.