Immunogenic formulations comprising oil bodies
AssigneeSemBioSys Genetics Inc.
InventorsHarm M. Deckers, Gijs van Rooijen, Joseph Boothe, Janis Goll, Maurice M. Moloney, Anthony B. Schryvers, Joenel Alcantara, Wendy A. Hutchins
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Abstract
The present invention provides novel adjuvants which comprise oil bodies. The invention also provides vaccine formulations comprising oil bodies and an antigen and methods for preparing the vaccines and the use of the vaccines to elicit an immune response.
Claims13
An immunogenic formulation comprising (a) an emulsion comprising substantially intact, washed oil bodies obtained from plant seeds, and (b) an antigen.
A method for preparing an immunogenic emulsion formulation comprising:
- (1) obtaining substantially intact oil bodies form a plant cell;
- (2) washing the oil bodies to obtain a washed oil body preparation;
- (3) formulating the washed oil body preparation into an emulsion;
- and
- (4) adding an antigen.
A method of eliciting an immune response comprising administering an effective amount of an immunogenic formulation comprising (a) an emulsion comprising substantially intact, washed oil bodies obtained from plant seeds, and (b) an antigen to an animal in need thereof.
Dependencies are inferred from the claim text.