AnB block copolymers containing poly (vinyl pyrrolidone) units, medical devices, and methods
AssigneeMedtronic, Inc.
InventorsMichael Eric Benz, Julie A. Alkatout, SuPing Lyu
Life of this patent
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Abstract
AnB block copolymers, wherein n is at least two, that include A blocks with poly(vinyl pyrrolidone) units and B blocks with urethane groups, urea groups, imide groups, amide groups, ether groups, ester groups, or combinations thereof, as well as medical devices and methods.
Claims70
A medical device comprising a surface comprising a thermoplastic AnB block copolymer, wherein the A block comprises poly(vinyl pyrrolidone) units and the B block is a long-chain organic polymeric connecting unit comprising urethane groups, urea groups, imide groups, amide groups, ester groups, ether groups, or combinations thereof, wherein n is at least two, and further wherein the long-chain organic connecting unit comprises 20 atoms or more.
A method of modifying a surface of a medical device, the method comprising:
- preparing a thermoplastic AnB block copolymer, wherein the A block comprises poly(vinyl pyrrolidone) units and the B block is a long-chain organic polymeric connecting unit comprising urethane groups, urea groups, imide groups, amide groups, ether groups, ester groups, or combinations thereof, wherein n is at least two, and further wherein the long-chain organic connecting unit comprises 20 atoms or more;
- and
- applying the AnB copolymer to the surface of the medical device.
A thermoplastic AnB block copolymer, wherein the A blocks comprise poly(vinyl pyrrolidone) units and the B block is a long-chain organic polymeric connecting unit comprising urethane groups, urea groups, imide groups, amide groups, ether groups, or combinations thereof, wherein n is at least two, and further wherein the long-chain organic connecting unit comprises 20 atoms or more.
A method of preparing a thermoplastic AnB block copolymer, the method comprising reacting a substantially monofunctional poly(vinyl pyrrolidone) with a functionalized B-block precursor comprising functional groups reactive with the functional groups of the poly(vinyl pyrrolidone) to form the thermoplastic AnB block copolymer, wherein the A blocks comprise poly(vinyl pyrrolidone) units and the B block is a long-chain organic polymeric connecting unit comprising urethane groups, urea groups, imide groups, amide groups, ether groups, or combinations thereof, wherein n is at least two, and further wherein the long-chain organic connecting unit comprises 20 atoms or more.
A method of preparing a thermoplastic AnB block copolymer, the method comprising reacting a substantially monofunctional poly(vinyl pyrrolidone) with functionalized B-block precursor reactants to form the thermoplastic AnB block copolymer, wherein the A blocks comprise poly(vinyl pyrrolidone) units and the B block is a long-chain organic polymeric connecting unit comprising urethane groups, urea groups, imide groups, amide groups, ether groups, or combinations thereof, wherein n is at least two, and further wherein the long-chain organic connecting unit comprises 20 atoms or more.
Dependencies are inferred from the claim text.