Method of reducing gastrointestinal side effects associated with orlistat treatment
AssigneeHoffmann-La Roche Inc.
InventorsPierre Barbier, Paul Hadvary, Hans Lengsfeld
Life of this patent
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Abstract
A pharmaceutical combination or composition containing a lipase inhibitor, preferably orlistat, and a bile acid sequestrant is useful for treating obesity.
Claims1
A method of reducing the gastrointestinal side effects associated with orlistat treatment, which comprises administering to a patient being treated with orlistat an amount of a bile salt sequestrant selected from the group consisting of cholestyramine, colestipol, colestimide, colesevelam, sevelamer, DEAE-cellulose, β-cyclodextrin, γ-cyclodextrin, guanidinoethylcellulose, and DEAE-Sephadex, effective to reduce the side effects associated with the orlistat treatment.
Dependencies are inferred from the claim text.