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US 6,749,832 B2Granted
Labelled ascorbic acid derivatives
AssigneeAmersham PLC
InventorsSusan Champion, Richard Pither
Life of this patent
Estimating the term…
Abstract
Compounds of formula (I) where: X1 is OH or SH or NH2 or —L-Z; X2 and X3 are the same or different and each is H, C1-4 alkyl, benzyl a protecting group or —L-Z, X4 is H or C1-4 alkyl, L is a linker comprising a chain of 0-10 atoms, Z is a group comprising a detectable moiety which comprise at least one detectable moiety are useful in the diagnosis and prognosis and radiotherapy of metastatic bone disease.
Claims14
A compound comprising:
- wherein:
- X1 is OH or SH or NH2 or —L-Z;
- X2 and X3 are the same or different and each is H, C1-4 alkyl, C1-4 fluoroalkyl, benzyl, a protecting group or —L-Z;
- X4 is H or C1-4 alkyl;
- L is a linker comprising a chain of 0-10 atoms;
- Z is a group comprising a detectable moiety that excludes 3H, 14C, 18F, and 11C;
- and wherein when neither of X2 or X3 is —L-Z that the compound further includes at least one detectable moiety.
4 more elements
Dependencies are inferred from the claim text.