Method and apparatus for analyzing mass spectrum
AssigneeJEOL Ltd.
InventorYutaka Takahashi
Life of this patent
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Abstract
A novel method and apparatus for analyzing a mass spectrum having the peaks of impurity adduct ions. The molecular weight of the sample molecule is determined based on the mass-to-charge ratios of the detected adduct ions. In addition, the peaks of the detected adduct ions are deleted from the detected data. Peaks of a given height are added to peak positions of molecular ions corresponding to the adduct ions. Then, a database search is performed.
Claims28
A method of analyzing a mass spectrum, comprising the steps of:
- comparing entered information about an ionization method, a detection polarity used by a mass spectrometer, and a mobile phase solvent with information registered in a database portion about ionization methods, detection polarities used by the mass spectrometer, mobile phase solvents, and adduct ions expected to be detected under these conditions;
- detecting peaks of adduct ions contained in data detected by the mass spectrometer;
- and
- determining the molecular weight of sample molecules based on detected mass-to-charge ratios of the adduct ions.
Apparatus for analyzing a mass spectrum, comprising:
- an input portion for entering information about an ionization method, a detection polarity used by a mass spectrometer, and a mobile phase solvent;
- a database portion having registered information about ionization methods, detection polarities used by the mass spectrometer, mobile phase solvents, and adduct ions having the possibility of being detected under these conditions, for comparison with the information entered from the input portion;
- and
- a control portion for detecting peaks of adduct ions within data detected by the mass spectrometer based on results of the comparison between the information entered from the input portion and the information registered in the database portion and determining the molecular weight of sample molecules based on detected mass-to-charge ratios of the adduct ions.
A method of analyzing a mass spectrum, comprising the steps of:
- comparing entered information about an ionization method, a detection polarity used by a mass spectrometer, and a mobile phase solvent with information registered in a database about ionization methods, detection polarities used by the mass spectrometer, mobile phase solvents, and adduct ions expected to be detected under these conditions;
- detecting peaks of adduct ions contained within data detected by the mass spectrometer;
- deleting the peaks of the adduct ions from the detected data;
- adding peaks of a given height to peak positions of molecular ions corresponding to the adduct ions;
- and
- then searching the detected data against said database.
Apparatus for analyzing a mass spectrum, comprising:
- an input portion for entering information about an ionization method, a detection polarity used by a mass spectrometer, and a mobile phase solvent;
- a database portion having a database holding registered information about ionization methods, detection polarities used by the mass spectrometer, mobile phase solvents, and adduct ions having the possibility of being detected under these conditions, for comparison with the information entered from the input portion;
- and
- a control portion for detecting peaks of adduct ions within data detected by the mass spectrometer based on the results of the comparison between the information entered from the input portion and the information registered in the database portion, deleting the peaks of the adduct ions from the detected ions, adding peaks of a given height to peak positions of the molecular ions corresponding to the adduct ions, and searching the detected data against the database.
Dependencies are inferred from the claim text.