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US 6,747,157 B2Granted
Processes for the preparation of oxo-oxazoline or alloamino acid derivatives
AssigneeShionogi & Co., Ltd.
InventorsMakoto Kobayashi, Haruo Koike, Masahiko Nagai
Life of this patent
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Abstract
A method for producing a compound represented by the general formula (I-A) or the general formula (I-B), comprising the following step: wherein R1 is an optionally substituted lower alkyl, and the like; R2 is a lower alkyl or an optionally substituted aralkyl, and the like; R3 is a lower alkyl, characterized in that a compound represented by the general formula (II-A) or the general formula (II-B) is treated with thionyl chloride.
Claims1
A method for production of a compound represented by the general formula (IV-A) or the general formula (IV-B), comprising the steps of:
- obtaining a compound represented by general formula (I-A) or the general formula (I-B) by treating a compound represented by general formula (II-A) or general formula (II-B) with thionyl chloride as follows:
- wherein R1 is an optionally substituted lower alkyl, an optionally substituted aryl, an alkynyl, or an optionally substituted heteroaryl;
- R2 is a lower alkyl, an optionally substituted aralkyl, or an optionally substituted heteroarylalkyl;
- and R3 is a lower alkyl;
- and subjecting the obtained compound represented by the general formula (I-A) or the general formula (I-B) to a hydrolysis as follows:
- wherein R1 and R3 are as described above;
- and then subjecting a compound represented by the general formula (III-A) or the general formula (III-B) to a hydrolysis as follows:
- wherein R1 is as described above.
5 more elements
Dependencies are inferred from the claim text.