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US 6,747,139 B1Granted
Nucleic acid encoding human thyrotropin receptor
AssigneeQuest Diagnostics Investments Incorporated
InventorsBasil Rapoport, Sandra McLachlan
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Abstract
Nucleic acids encoding human thyrotropin receptor and related methods are disclosed. The nucleic acids may have nucleotides deleted and/or replaced to modify the amino acid sequence of human thyrotropin receptor.
Claims3
A recombinant nucleic acid sequence identical to SEQ ID NO:
- 54 with the exception of having;
- A nucleic acid sequence region encoding for amino acids 317 to 366 deleted from said recombinant nucleic acid sequence.
A recombinant nucleic acid sequence identical to SEQ ID NO:
- 54 with the exception of having:
- a nucleic acid sequence region encoding for GQE at position 367 to 369 of amino acid sequence SEQ ID NO:
- 53 replaced with a nucleic acid sequence region encoding for NET or NQT at the 376 to 369 position instead.
A recombinant nucleic acid sequence identical to SEQ ID NO:
- 54 with the exception of having:
- a nucleic acid sequence region encoding for amino acids 317 to 366 deleted from said recombinant nucleic acid sequence;
- and
- a nucleic acid sequence region encoding for GQE at position 367 to 369 of amino acid sequence SEQ ID NO:
- 53 replaced with a nucleic acid sequence region encoding for NET or NQT at the 376 to 369 position instead.
2 more elements
Dependencies are inferred from the claim text.