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US 6,747,138 B1Granted
Methods and compositions for regulating Fas-associated apoptosis
AssigneeThe Regents of the University of Michigan
InventorsVishva M. Dixit, Karen O'Rourke
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Abstract
This invention provides a novel purified mammalian protein designated FADD having the ability to bind the cytoplasmic region or domain of the Fas receptor. Also provided are nucleic acid molecules that encode the mammalian protein which binds the intracellular domain of Fas as well as methods for using the proteins and nucleic acid molecules.
Claims2
An isolated nucleic acid molecule comprising a sequence encoding a polypeptide comprising amino acid residues 111 to 170 of SEQ ID NO:2.
Dependencies are inferred from the claim text.