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US 6,743,448 B2Granted
Topical testosterone formulations and associated methods
OwnerAbraham H. Krygerinventor
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Abstract
A topical testosterone formulation is disclosed. In one aspect, the formulation may include a therapeutically effective amount of micronized testosterone, an arginine ingredient, and a tocopherol ingredient admixed with a poloxamer lecithin organogel. Additional ingredients may be included, such as melatonin, oxytocin, DHEA, and progesterone.
Claims22
A method of minimizing aromatic conversion of testosterone to an estrogen during testosterone supplementation therapy a patient in need thereof comprising the steps of:
- coadministering to the skin of a subject from a topical formulation, a therapeutically effective amount of testosterone, and an amount of tocopherol that is sufficient to minimize aromatization of the testosterone to an estrogen.
Dependencies are inferred from the claim text.