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US 6,743,447 B2Granted
Pulverulent mannitol and process for preparing it
AssigneeRoquette Freres
InventorsErik Labergerie, Philippe Lefevre, José Lis
Life of this patent
Estimating the term…
Abstract
The present invention concerns pulverulent mannitol characterized in that it has an average diameter of between 60 and 200 μm, preferably of between 80 and 180 μm, a packed density, determined according to a Test A, of between 0.65 and 0.85 g/ml, preferably of between 0.7 and 0.8 g/ml and a flow factor of at least 60, preferably of between 60 and 90a process for obtaining and using the said pulverulent mannitol as an excipient in preparations intended in particular for the pharmaceutical field, and especially as a powder for filling hard capsules.
Claims7
A pulverulent mannitol having:
- an average diameter of between 80 and 180 μm;
- a packed bulk density, determined according to the method specified in the operating instructions for the HOSOKAWA P.T.N powder tester, of between 0.70 and 0.80 g/ml;
- a flow factor of at least 60.
Dependencies are inferred from the claim text.