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US 6,743,430 B1Granted
Multicomponent vaccine containing clostridial and non-clostridial organisms in a low dose
OwnerRichard E. Parizek, Lonny E. Vlieger +3inventors
InventorsRichard E. Parizek, Lonny E. Vlieger, Sharon A. Bryant, Stuart K. Nibbelink, Michael J. McGinley
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Abstract
Disclosed herein is a multicomponent low dose vaccine comprising a safe and immunogenically effective combination of a protective antigen component or components of clostridial organism, a protective antigen component of a non-clostridial organism and an adjuvant.
Claims9
A multicomponent vaccine for cattle, comprising:
- an immunogenically effective combination of a protective antigen component from at least 6 clostridial organisms,
- a protective antigen component from a non-clostridial organism, which is
- Hemophilus somnus, and
- further comprising an adjuvant wherein the vaccine is in a low dose volume of about 2.0 mL or less.
1 more element
A multicomponent vaccine for cattle, comprising:
- a safe and immunogenically effective combination of a protective antigen component from 6 clostridial organisms which are Cl. chauvoei, Cl. septicum, Cl novyi, Cl. perfringens type C, Cl. perfringens type D, and Cl. sordellii;
- a protective antigen component from a non-clostridial organism, which, is H. somnus and
- an adjuvant, wherein the vaccine is in a low dose volume of about 2.0 mL or less.
A multicomponent vaccine for cattle, comprising:
- a safe and immunogenically effective combination of a protective antigen component from 7 clostridial organisms which are Cl. chauvoei, Cl. septicum, Cl novyi, Cl. perfringens type C, Cl. perfringens type D, Cl. haemolyticum and Cl. sordellii;
- a protective antigen component from a non-clostridial organism, which is H. somnus, and
- an adjuvant, wherein the vaccine is in a low dose volume of about 2.0 mL or less.
Dependencies are inferred from the claim text.