Prevention and treatment of amyloidogenic disease
AssigneeNeuralab Limited
InventorDale B. Schenk
Life of this patent
Estimating the term…
Abstract
The invention provides improved agents and methods for treatment of diseases associated with amyloid deposits of Aβ in the brain of a patient. Such methods entail administering agents that induce a beneficial immunogenic response against the amyloid deposit. The methods are useful for prophylactic and therapeutic treatment of Alzheimer's disease. Preferred agents including N-terminal fragments of Aβ and antibodies binding to the same.
Claims19
A method of prophylactically or therapeutically treating Alzheimer's disease, comprising administering to the patient an effective dosage of a pharmaceutical composition comprising an antibody that specifically binds to an epitope within residues 1-12 of Aβ wherein the isotype of the antibody is human IgG1.
Dependencies are inferred from the claim text.