Substitution infusion fluid and citrate anticoagulation
AssigneeEdwards Lifesciences Corporation
InventorPe Chou Chang
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AssigneeEdwards Lifesciences Corporation
InventorPe Chou Chang
Estimating the term…
The invention relates to a substitution infusion fluid for hemofiltration of a specific composition. The use of said substitution infusion fluid significantly reduces the risk of the occurrence of abnormalities in a patient undergoing pure hemofiltration. The invention also relates to process for pure hemofiltration of blood wherein said substitution infusion fluid is used. The invention also relates to a matching citrate anticoagulation fluid of a specific composition. The invention also relates to a process for pure hemofiltration of blood wherein said substitution infusion fluid is used in combination with said citrate anticoagulation fluid. The use of said substitution infusion fluid in combination with said citrate anticoagulation fluid significantly further reduces the risk of the occurrence of abnormalities in a patient undergoing pure hemofiltration.
An a queous substitution infusion fluid for pure hemofiltration of blood using citrate as anticoagulant comprising:
An aqueous substitution infusion fluid for pure hemofiltration of blood using citrate as anticoagulant comprising about 100 mmol/L of sodium ions, about 2.1 mmol/L of calcium ions, about 2.2 mmol/L of potassium ions, about 0.6 mmol/L of phosphate ions, about 0.8 mmol/L of magnesium ions, about 7.0 mmol/L of glucose, less than 3.1 mmol/L of acetate ions, and chloride ions to keep electrochemical balance.
An aqueous substitution infusion fluid for pure hemofiltration of blood using citrate as anticoagulant comprising about 107 mmol/L of sodium ions, about 2.3 mmol/L of calcium ions, about 2.5 mol/L of potassium ions, about 0.8 mmol/L of phosphate ions, about 0.9 mmol/L of magnesium ions, about 6.4 mmol/L of glucose, less than 5.5 mmol/L of acetic acid, and chloride ions to keep electrochemical balance.
An aqueous substitution infusion fluid for pure hemofiltration of blood using citrate as anticoagulant comprising about 118 mmol/L of sodium ions, about 2.3 mmol/L of calcium ions, about 2.6 mmol/L of potassium ions, about 0.8 mmol/L of phosphate ions, about 0.9 mmol/L of magnesium ions, about 6.5 mmol/L of glucose, less than 5.5 mmol/L of acetic acid, and chloride ions to keep electrochemical balance.
A citrate anticoagulation solution for anticoagulation of circulating blood during pure hemofiltration, comprising between 19 and 135 mmol/L of citric acid and between 106 and 290 mmol/L of trisodium citrate.
A citrate anticoagulation solution for anticoagulation during pure hemofiltration of blood being an aqueous solution comprising about 38 mmol/L of citric acid and about 212 mmol/L of trisodium citrate.
Dependencies are inferred from the claim text.