Cardiac disease treatment and device

A device for treating cardiac disease of a heart having an upper portion and a lower portion divided by an A-V groove, the device comprising:

• a. a jacket of flexible material defining a volume between an upper end and a lower end, the jacket adapted to be secured to the heart and adapted to be adjusted on the heart to snugly conform to an external geometry of the heart to constrain expansion of the heart during diastole and permit substantially unimpeded contraction of the heart during systole;
• b. a non-adherent lining in association with the jacket;
• and
• c. a delivery source for the delivery of one or more therapeutic agents to the surface of the heart.

A method for treating cardiac disease, the method comprising:

• a. surgically accessing the heart;
• b. applying a treatment device on the heart, the device comprising:
• 1) a jacket of flexible material defining a volume between an upper end and a lower end, the jacket adapted to be secured to the heart and adapted to be adjusted on the heart to snugly conform to an external geometry of the heart to constrain circumferential expansion of the heart during diastole and permit substantially unimpeded contraction of the heart during systole;
• and
• 2) a non-adherent lining in association with the jacket, wherein the non-adherent lining is provided in the form of one or more ribs extending from a base to an apex of the heart;
• c. securing the treatment device to the heart;
• and
• d. surgically closing access to the heart while leaving the treatment device on the heart.

A method for treating cardiac disease, the method comprising:

• a. surgically accessing the heart;
• b. applying a treatment device on the heart, the device comprising:
• 1) a jacket of flexible material defining a volume between at upper end and a lower end, the jacket adapted to be secured to the heart and adapted to be adjusted on the heart to snugly conform to an external geometry of the heart to constrain circumferential expansion of the heart during diastole and permit substantially unimpeded contraction of the heart during systole;
• 2) a non-adherent lining;
• and
• 3) a delivery source for delivery of one or more therapeutic agents to the surface of the heart;
• c. securing the treatment device to the heart;
• and
• d. surgically closing access to the heart while leaving the treatment device on the heart.

A device for treating cardiac disease of a heart having an upper portion and a lower portion divided by an A-V groove, the device comprising:

• a. a jacket of flexible material defining a volume between an upper end and a lower end, the jacket adapted to be secured to the heart and adapted to be adjusted on the heart to snugly conform to an external geometry of the heart to constrain expansion of the heart during diastole and permit substantially unimpeded contraction of the heart during systole;
• b. a non-adherent coating in association with the jacket;
• and
• c. a delivery source for the delivery of one or more therapeutic agents to the surface of the heart.

A method for treating cardiac disease, the method comprising:

• a. surgically accessing the heart;
• b. applying a treatment device on the heart, the device comprising:
• 1) a jacket of flexible material defining a volume between an upper end and a lower end, the jacket adapted to be secured to the heart and adapted to be adjusted on the heart to snugly conform to an external geometry of the heart to constrain circumferential expansion of the heart during diastole and permit substantially unimpeded contraction of the heart during systole;
• and
• 2) a non-adherent coating in association with the jacket, wherein the non-adherent coating is configured to contact only selected areas of the heart;
• c. securing the treatment device to the heart;
• and
• d. surgically closing access to the heart while leaving the treatment device on the heart.

A method for treating cardiac disease, the method comprising:

• a surgically accessing the heart;
• b. applying a treatment device oil the heart, the device comprising:
• 1) a jacket of flexible material defining a volume between an upper end and a lower end, the jacket adapted to be secured to the heart and adapted to be adjusted on the heart to snugly conform to an external geometry of the heart to constrain circumferential expansion of the heart during diastole and permit substantially unimpeded contraction of the heart during systole;
• and
• 2), a non-adherent coating in association with the jacket, wherein the non-adherent material is provided in the form of one or more ribs extending from a base to an apex of the heart;
• c. securing the treatment device to the heart;
• and
• d. surgically closing access to the heart while leaving the treatment device on the heart.

A method for treating cardiac disease, the method comprising:

• a. surgically accessing the heart;
• b. applying a treatment device on the heart, the device comprising:
• 1) a jacket of flexible material defining a volume between an upper end and a lower end, the jacket adapted to be secured to the heart and adapted to be adjusted on the heart to snugly conform to an external geometry of the heart to constrain circumferential expansion of the heart during diastole and permit substantially unimpeded contraction of the heart during systole;
• 2) a non-adherent coating in association with the jacket;
• and
• 3) a delivery source for delivery of one or more therapeutic agents to the surface of the heart;
• c. securing the treatment device to the heart;
• and
• d. surgically closing access to the heart while leaving the treatment device on the heart.