Method for plasma charging a probe

A method for electrically charging a probe, cannula, pin tool or other similar component or plurality of such components made of any material of a fluid dispensing device and coated with one or more additional materials or treatments used to pipet small volumes of fluids by plasma technology comprising the following steps:

• placing such coated probe, cannula, pin tool or other similar component or plurality of such components with a physical coating or permanent surface treatment to be charged in a space that plasma is generated by a plasma generating device;
• applying electromagnetic energy to the plasma generating device, thereby molecularly disassociating the gas, thus creating charged ions, free electrons, and free radicals, and charging the surface by the charged ions and free radicals attaching to the probe, cannula, pin tool or other similar component or plurality of such components;
• removing the charged probe, cannula, pin tool or other similar component or plurality of such components from the area of plasma generation, whereby the charged probe, cannula, pin tool or other similar component or plurality of such components can pipette compounds in small volumes.

A method for electrically charging the surfaces of a fluid containing device, such as, but not limited to, a tube or microplate made of any material, with one or a plurality of containment wells or fluid processing surface, made of any material including but not limited to plastic, composite, glass or silicon, by plasma technology for use in manipulating small volumes of fluids comprising the following steps:

• placing such container, having a tube like structure or wells for containing such fluid or a surface to place drops of fluids into a position so as to be exposed appropriately to the plasma;
• applying electromagnetic energy to the plasma generating device, thereby molecularly disassociating the gas, thus creating charged ions, free electrons, and free radicals, and charging the probe by the charged ions and free radicals attaching to the surfaces to be treated;
• moving or leaving in place the containing device or surface for the dispensing of small volumes of fluid, or removing or leaving in place the containing device or surface without further processing.