Concentrated formulations and methods for neutralizing chemical and biological toxants
AssigneeSandia Corporation
InventorsMark D. Tucker, Rita G. Betty, Maher E. Tadros
Life of this patent
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Abstract
A formulation and method of making and using that neutralizes the adverse health effects of both chemical and biological toxants, especially chemical warfare (CW) and biological warfare (BW) agents. The aqueous formulation is non-toxic and non-corrosive and can be delivered as a long-lasting foam, spray, or fog. The formulation includes solubilizing compounds that serve to effectively render the CW or BW toxant susceptible to attack, so that a nucleophillic agent can attack the compound via a hydrolysis or oxidation reaction. The formulation can kill up to 99.99999% of bacterial spores within one hour of exposure.
Claims111
An aqueous decontamination formulation for use in the neutralization of a chemical or biological toxant, comprising:
- a cationic surfactant;
- a cationic hydrotrope;
- a reactive compound selected from the group consisting of nucleophilic compounds, oxidizing compounds, and combinations thereof;
- a fatty alcohol having a concentration from greater than 1 wt. % to 2 wt %;
- and water.
An aqueous decontamination formulation for use in the neutralization of a chemical or biological toxant, comprising:
- a cationic surfactant;
- a cationic hydrotrope;
- a reactive compound selected from the group consisting of nucleophilic compounds, oxidizing compounds, and combinations thereof;
- and
- water;
- wherein the weight percentage ratio of surfactant to hydrotrope is from 0.5 to 3.5.
An aqueous decontamination formulation for use in the neutralization of a chemical or biological toxant, comprising:
- 4-6 wt % of a cationic surfactant;
- 1-3 wt % of a cationic hydrotrope;
- 0.5-2 wt % of a fatty alcohol;
- 0.05-0.1 wt % of a cationic water soluble polymer;
- 0.5-1.5 wt % of a short chain alcohol;
- 1-2 wt % of a glycol ether compound;
- 4 wt % of a bicarbonate salt;
- 4 wt % of a hydrogen peroxide;
- and
- water.
The formulation of clam 42, comprising:
- about 4.2 wt % a mixture of benzyl (C12-C16) alkyldimethylammonium chlorides;
- about 1.4 wt % pentamethyltallow alkyltrimethylenediammonium dichloride;
- about 0.07 wt % Guar Gum, 2-hydroxypropyl ether;
- about 1.3 wt % 1-Dodecanol;
- about 0.5 wt % 1-Tetradecanol;
- about 0.4 wt % Isobutanol;
- about 0.8 wt % Isopropanol;
- about 1.5 wt % Diethylene Glycol Monobutyl Ether;
- about 4.0 wt % Potassium Bicarbonate;
- about 4.0 wt % Hydrogen Peroxide;
- and
- water.
An aqueous decontamination formulation for use in the neutralization of a chemical or biological toxant, comprising:
- about 2.6 wt % of a cationic surfactant;
- about 3.3 wt % of a cationic hydrotrope;
- about 0.8 wt % of a fatty alcohol;
- about 0.1 wt % of a cationic water soluble polymer;
- about 2.1 wt % of a short chain alcohol;
- about 1.6 wt % of a glycol ether compound;
- about 4 wt % of a bicarbonate salt;
- about 4 wt % of hydrogen peroxide;
- and
- water.
An aqueous, non-foaming decontamination formulation for use in the neutralization of a chemical or biological toxant, comprising:
- 0.1-10 wt% of a cationic surfactant;
- 0.1-10 wt % of a cationic hydrotrope;
- 0.1-10 wt % of a bicarbonate salt;
- 0.1-10% of hydrogen peroxide;
- and
- water.
A binary kit system consisting of two components that, when mixed together, makes an aqueous decontamination formulation for use in the neutralization of a chemical or biological toxant, the system comprising:
- a first premixed component, Part A, comprising an aqueous mixture of a cationic surfactant, a cationic hydrotrope, and a bicarbonate salt, wherein Part A has a concentration of 30-92 wt%;
- and
- a second component, Part B, comprising hydrogen peroxide.
A ternary kit system consisting of three components that, when mixed together, makes an aqueous decontamination formulation for use in the neutralization of a chemical or biological toxant, the system comprising:
- a first premixed component, Part A, comprising an aqueous mixture of a cationic surfactant, and a cationic hydrotrope, wherein Part A has a concentration of 14-30 wt%;
- a second component, Part B, comprising hydrogen peroxide;
- and
- a third component, Part C, comprising a bicarbonate salt.
A ternary kit system consisting of three components that, when mixed together, makes an aqueous non-foaming decontamination formulation for use in the neutralization of a chemical or biological toxant, the system comprising:
- a first premixed component, Part A, comprising an aqueous mixture of a cationic surfactant and a cationic hydrotrope, with no amount of cationic water-soluble polymer, wherein Part A has a concentration of 6-30 wt%;
- a second component, Part B, comprising hydrogen peroxide;
- and
- a third component, Part C, comprising a bicarbonate salt.
A binary kit system consisting of two components that, when mixed together, makes an aqueous non-foaming decontamination formulation for use in the neutralization of a chemical or biological toxant, the system comprising:
- a first premixed component, Part A, comprising an aqueous mixture of a cationic surfactant, a cationic hydrotrope, and bicarbonate salt, with no amount of cationic water-soluble polymer, wherein Part A has a concentration of 23-30 wt%;
- and
- a second component, Part B, comprising hydrogen peroxide.
A method of manufacturing a premixed concentrate 30-50 wt% for use as Part A of a binary kit system, for use in making up a decontamination formulation for use in the neutralization of a chemical or biological toxants;
- comprising mixing together at least the following constituents:
- 0.1-10 wt% of a cationic surfactant;
- 0.1-10 wt% of a cationic hydrotrope;
- 0.05-10 wt% of a water-soluble polymer;
- 0.1-10 wt% of a bicarbonate salt;
- and
- a sufficient amount of water.
A method of manufacturing a premixed concentrate of 14-30 wt% for use as Part A of a ternary kit system, for use in making up a decontamination formulation for use in the neutralization of a chemical or biological toxants;
- comprising mixing together at least the following constituents:
- 0.1-10 wt% of a cationic surfactant;
- 0.1-10 wt% of a cationic hydrotrope;
- 0.05-10 wt% of a water-soluble polymer;
- and
- a sufficient amount of water.
Dependencies are inferred from the claim text.