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US 6,723,709 B1Granted
Biomaterials for preventing post-surgical adhesions comprised of hyaluronic acid derivatives
AssigneeFidia Advanced Biopolymers S.r.l.
InventorsDaniele Pressato, Alessandra Pavesio, Lanfranco Callegaro
Life of this patent
Estimating the term…
Abstract
New biomaterials essentially constituted by esterified derivatives of hyaluronic acid or by cross-linked derivatives of hyaluronic acid for use in the surgical sector, particularly for use in the prevention of post-surgical adhesion.
Claims15
A composite biomaterial comprised of:
- a benzyl ester of hyaluronic acid, wherein 80% of the carboxyl groups of hylauronic acid are esterified with a benzyl radical and up to 20% of the carboxyl groups are esterified with the alkyl radical of a C10 to C20 aliphatic alcohol, and
- wherein said biomaterial is in the form of a gel, a flat membrane or mesh, a woven or non-woven tissue, or combinations thereof and wherein said biomaterials prevent the surgical adhesion of tissue.
A method for preventing surgical adhesions of tissue which comprises applying to tissue involved in surgery a biomaterial comprised of:
- a benzyl ester of hyaluronic acid wherein 80% of the carboxyl groups of hyaluronic acid are esterified with a benzyl radical and up to 20% of the carboxyl groups are esterified with the alkyl radical of a C10 to C20 aliphatic alcohol.
Dependencies are inferred from the claim text.