Treating disorders by application of insulin-like growth factors and analogs
AssigneeCephalon, Inc.
InventorsMichael E. Lewis, Kathleen V. Callison, Frank Baldino
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Abstract
A method of enhancing the survival of neuronal cells in a mammal, the cells being at risk of dying, the method comprising administering to the mammal an effective amount of one of the following substances: IGF-I; a functional derivative of IGF-I; IGF-II; a functional derivative of IGF-II; IGF-III; or a functional derivative of IGF-III.
Claims5
A method of treating a mammal subject to a neurological disease comprising administering to said mammal an amount of insulin-like growth factor I effective to enhance the survival of non-mitotic neuronal cells at risk of dying.
A method for enhancing the survival of non-mitotic neuronal cells in a mammal, said cells being at risk of dying, said method comprising administering to said mammal an effective amount of insulin-like growth factor I.
A method for preventing non-mitotic neuronal cell death in a mammal resulting from aging, injury, or disease, said method comprising administering an effective amount of insulin-like growth factor-I.
Dependencies are inferred from the claim text.