Process for the production of alkanediol derivative
AssigneeIhara Chemical Industry Co., Ltd.
InventorsYoshikazu Kimura, Yukio Uchida, Shuichi Fujimoto
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AssigneeIhara Chemical Industry Co., Ltd.
InventorsYoshikazu Kimura, Yukio Uchida, Shuichi Fujimoto
Estimating the term…
The present invention provides a process for producing an alkanediol derivative represented by the general formula (II) from an ester compound represented by the general formula (I), safely without giving rise to racemization. The present invention lies in a process for producing an alcohol derivative represented by the following general formula (II): (wherein R2 and R3 are each independently a hydrogen atom or an alkyl group having 1 to 4 carbon atoms; X is a hydrogen atom or a protecting group for hydroxyl group; and n is 0 or 1), which process comprises reducing an ester compound represented by the following general formula (I): (wherein R1 is an alkyl group having 1 to 4 carbon atoms; and R2, R3, X and n have the same definitions as given above) with sodium borohydride in a mixed solvent of at least one kind of solvent selected from the group consisting of aromatic hydrocarbons, aliphatic hydrocarbons and alicyclic hydrocarbons and a primary alcohol.
A process for producing an alcohol derivative represented by the following general formula (II):
A process for producing an alcohol derivative represented by the following general formula (II):
A process for producing an alcohol derivative represented by the following general formula (II):
Dependencies are inferred from the claim text.