# US 6,720,412 B2 · Human thrombospondin repeat proteins and polynucleotides encoding the same

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- Number: US 6,720,412 B2
- Document ID: US6720412B2
- Status: Granted
- Kind: B2
- Application number: 09/784,358
- Filed: 2001-02-15
- Published: 2002-07-25
- Granted: 2004-04-13
- Earliest claimed: 2000-02-17
- Assignees: Lexicon Genetics Incorporated
- Inventors: Gregory Donoho; John Scoville; C. Alexander Turner, Jr.; Glenn Friedrich; Brian Zambrowicz; Arthur T. Sands
- Web page: https://patentgrep.com/patent/US6720412B2

## CPC

- C07K 14/78: Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
- C07K: PEPTIDES (peptides in foodstuffs A23; obtaining protein compositions for foodstuffs, working-up proteins for foodstuffs A23J; preparations for medicinal purposes A61K; peptides containing beta-lactam rings C07D; cyclic dipeptides not having in their molecule any other peptide link than those which form their ring, e.g. piperazine-2,5-diones, C07D; ergot alkaloids of the cyclic peptide type C07D519/02; macromolecular compounds having statistically distributed amino acid units in their molecules, i.e. when the preparation does not provide for a specific; but for a random sequence of the amino acid units, homopolyamides and block copolyamides derived from amino acids C08G69/00; macromolecular products derived from proteins C08H1/00; preparation of glue or gelatine C09H; single cell proteins, enzymes C12N; genetic engineering processes for obtaining peptides C12N15/00; compositions for measuring or testing processes involving enzymes C12Q; investigation or analysis of biological material G01N33/00)

## Abstract

Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.

## Claims

### Claim 1

An isolated nucleic acid molecule comprising the nucleotide sequence of SEQ ID NO:1.

### Claim 2

An isolated nucleic acid molecule comprising a nucleotide sequence that encodes the amino acid sequence shown in SEQ ID NO: 2.

### Claim 3 (depends on 2)

A recombinant expression vector comprising the isolated nucleic acid molecule of claim 2.

### Claim 4 (depends on 3)

The recombinant expression vector of claim 3, wherein the isolated nucleic acid molecule comprises the nucleotide sequence of SEQ ID NO:1.

### Claim 5 (depends on 3)

A host cell comprising the recombinant expression vector of claim 3.