US 6,720,347 B2Granted

Carbon substituted aminothiazole inhibitors of cyclin dependent kinases

AssigneeBristol-Myers Squibb Company

InventorsDavid B. Rawlins, S. David Kimball, Kyoung S. Kim, Raj N. Misra, Kevin R. Webster

Life of this patent

Estimating the term…

Abstract

Compounds of the formula and pharmaceutically acceptable salts thereof, wherein R1 and A are defined herein, are protein kinase inhibitors and are useful in the treatment of proliferative diseases, for example, cancer, inflammation and arthritis. They may also be useful in the treatment of Alzheimer's disease and cardiovascular disease.

Claims2

Dependent claims

N-[(E)-5-(2-(5-t-Butyl-oxazol-2-yl)-vinyl)-thiazol-2-yl]-acetamide or a pharmaceutically acceptable salt thereof.

Dependencies are inferred from the claim text.

Facts

Application: 10/112,133Filed 29 Mar 2002 · division
Priority: 18 Jun 1998
Published: US 2002/0165259 A17 Nov 2002
Granted: 13 Apr 2004
Term ends: Not estimatedThe source records don’t support an estimate.

Classification8 codes

C07D 231/12
Having two or three double bonds between ring members or between ring members and non-ring members: with only hydrogen atoms, hydrocarbon or…
C07D 233/56
Having two double bonds between ring members or between ring members and non-ring members: with only hydrogen atoms or radicals containing only…
C07D 249/08
Not condensed with other rings: 1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
C07D 277/46
Acylated amino or imino radicals: by carboxylic acids, or sulfur or nitrogen analogues thereof

Family

Application60/089,747Us provisional application · filed 18 Jun 1998
Application09/329,616Parent of this division · filed 10 Jun 1999
US 2002/0165259 A1Pre-grant publication · published 7 Nov 2002
US 6,407,124 B1Parent of this division
US 6,720,347 B2This patent

From the US filing history. Foreign family members aren’t listed.

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