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US 6,720,157 B2Granted
Chips having elevated sample surfaces
AssigneeZyomyx, Inc.
InventorsPierre F. Indermuhle, Frank G. Zaugg, Peter Wagner, Steffen Nock
Life of this patent
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Abstract
A chip is disclosed. The chip includes a base including a non-sample surface and at least one structure includes a pillar. Each structure includes a sample surface that is elevated with respect to the non-sample surface and each structure may be adapted to receive a sample.
Claims19
A method comprising:
- a) supplying a plurality of liquids containing respectively different components to respective channels in a dispenser;
- b) aligning sample surfaces on a plurality of structures on a base of a chip with the channels in the dispenser by moving at least one of the chip and the dispenser, wherein the plurality of structures comprise a plurality of pillars, and wherein the sample surfaces are at ends of the structures;
- c) simultaneously dispensing the plurality of liquids in the channels onto the sample surfaces;
- and
- d) binding the different components to the sample surfaces.
2 more elements
A method comprising:
- a) supplying a plurality of liquids to respective channels in a dispenser, wherein each of the channels includes a passive valve and wherein the flow of each liquid in each channel stops at the passive valve;
- b) aligning sample surfaces of a plurality of structures of a sample chip with the plurality of channels, wherein each structure comprises a pillar, and wherein at least one of the sample chip and the dispenser move during aligning;
- and
- c) simultaneously contacting the sample surfaces, and the liquids in the channels while the sample surfaces are in, or are positioned at ends of, the channels.
1 more element
Dependencies are inferred from the claim text.