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Assigneeesparma GmbH
InventorsWolfgang Wohlrab, Reinhard Neubert, Christoph Huschka, Peter-Jürgen Müller, Jörg-Herman Ozegowski, Dieter Koegst, Gerhard Fries
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The invention relates to an agent for treating skin diseases and/or functional disorders of the skin on the basis of different medicaments and/or auxiliary substances through promotion of penetration from topical formulations into the skin. According to the invention, the agent is composed of a hyaluronate lyase produced by microbial means and a medicament, preferably a hydrophilic medicament and/or auxiliary substances in different galenic formulations including colloidal carrier systems. The areas of application for the invention in human and veterinary medicament relate to the treatment, prophylaxis and/or metaphylaxis of skin diseases, functional disorders of the skin, the processes of skin ageing and dry skin conditions.
A composition for topical application on human or animal skin and/or mucosa, comprising at least one active substance and hyaluronate lyase in concentrations of 100 IU to 100000 IU per g formulation as a penetration enhancer, wherein the hyaluronate lyase is obtained from a micro-organism by microbial fermentation and wherein the hyaluronate lyase belongs to EC 4.2.2.1.
Dependencies are inferred from the claim text.