Magnetic particle composition
AssigneeDNA Research Innovations Limited
InventorMatthew John Baker
Life of this patent
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Abstract
A magnetic particle composition which can be used for separating biomolecules comprises magnetic materials of preferably less than five micron diameter bound to a negatively charged ion exchanger. The composition can be used to separate DNA from mixtures and to separate out cell debris.
Claims29
A magnetic particle composition which consists essentially of a magnetic material combined with a negatively charged ion exchanger, wherein the particles have a diameter between 20 microns and 1 mm and wherein the composition is formed by mixing a powder of a magnetic material with a powder of a negatively charged ion exchanger.
A method of forming a magnetic particle composition consisting essentially of a magnetic material combined with a negatively charred ion exchanger, wherein the particles have a diameter between 20 microns and 1 mm, the method comprising mixing a powder of a magnetic material with a powder of a negatively charged ion exchanger.
A method of separating biomolecules from mixtures containing them, the method comprising:
- contacting a liquid suspension of the biomolecules with a magnetic particle composition;
- forming a suspension of said magnetic particle composition and said suspension of biomolecules in which the magnetic particle composition binds to the biomolecules;
- and
- applying a magnetic field to the suspension to separate out the magnetic particles having the biomolecules bind thereto;
- wherein said magnetic particle composition consisting essentially of a magnetic material combined with a negatively charged ion exchanger and wherein the particles have a diameter between 20 microns and 1 mm and wherein the composition is formed by mixing a powder of a magnetic material with a powder of a negatively charged ion exchanger.
Dependencies are inferred from the claim text.