Implant for subcutaneous or intradermal injection
AssigneeAventis Pharmaceuticals Holdings, Inc.
InventorsJérôme Asius, Hatem Fessi, Franck Gouchet, Bénédicte Laglenne, Elisabeth Laugier-Laglenne
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Abstract
The invention concerns an injection implant for filling up wrinkles, thin lines, skin cracks and scars, for reparative or plastic surgery, aesthetic dermatology, and for filling up gums in dental treatment. The invention concerns the use of biologically absorbable polymer microspheres or microparticles suspended in a gel. Said suspension is produced either ready-for-use or freeze-dried. The biological absorbability of the microspheres is controlled and enables the production of implants having well defined persistence and deliberately limited to 3 years.
Claims20
A bioresorbable injectable implant for human administration consisting essentially of:
- bioresorbable microspheres or microparticles suspended in a gel consisting essentially of materials of non-animal origin,
- said microspheres or microparticles consisting of at least one polymer of non-animal origin selected from the group consisting of lactic acid polymers, glycolic acid polymers, and lactic acid-glycolic acid co-polymers.
A bioresorbable injectable implant, free of materials of animal origin, for human administration comprising:
- microparticles, free of materials of animal origin, comprising:
- at least one polymer selected from the group consisting of lactic acid polymers, glycolic acid polymers, lactic acid-glycolic acid co-polymers, and mixtures thereof;
- and
- a gel, free of materials of animal origin, comprising:
- water for injection,
- from about 0.1 to about 7.5% (wt/wt) of an injectable gelling agent, and
- a surfactant,
- wherein said microparticles are suspended in said gel, and
- wherein said gel is resorbable within about two months.
Dependencies are inferred from the claim text.