US 6,713,302 B1Granted

Growth differentiation factor-6

AssigneeThe Johns Hopkins University School of Medicine

InventorsSe-Jin Lee, Thanh Huynh

Life of this patent

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Abstract

Growth differentiation factor-6 (GDF-6) is disclosed along with its polynucleotide sequence and amino acid sequence. Also disclosed are diagnostic and therapeutic methods of using the GDF-6 polypeptide and polynucleotide sequences.

Claims18

Dependent claims

A method for suppressing GDF-6 activity in a placental cell comprising contacting the cell in vitro with a GDF-6 antisense sequence, which suppresses the GDf-6 activity, wherein the GDF-6 antisense sequence comprises at least 15 nucleotides which are fully complementary to SEQ ID NO:5.

Dependencies are inferred from the claim text.

Facts

Application: 09/619,061Filed 18 Jul 2000 · division
Priority: 9 Jul 1993
Granted: 30 Mar 2004
Term ends: Not estimatedThe source records don’t support an estimate.

Classification7 codes

A61K 51/1018
Antibodies or immunoglobulins; Fragments thereof , the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised…
C07K 14/475
From animals; from humans: growth factors; Growth regulators
C07K 14/495
Growth factors; Growth regulators: transforming growth factor [TGF]
C07K 16/22
Against material from animals or humans: against growth factors ; against growth regulators

Family

Application08/089,300Parent of this continuation · filed 9 Jul 1993
PCT/US94/07762Parent of this division · filed 8 Jul 1994
Application09/097,616Parent of this division · filed 15 Jun 1998
US 5,770,444 AParent of this division · filed 23 Jun 1998
US 6,090,563 AParent of this division · filed 18 Jul 2000
Application08/581,529Parent of this division
Application08/581,529Parent of this continuation
US 6,713,302 B1This patent

From the US filing history. Foreign family members aren’t listed.

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