Phytochemotherapy for cancer
AssigneeJackson State University
InventorErnest B. Izevbigie
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Abstract
The present invention provides for a novel anti-neoplastic pharmaceutical composition. Specifically, the present invention provides for phytochemotherapeutic compositions produced from aqueous extracts (and fractions thereof), derived from Vernonia amygdalina leaves. These pharmaceutical compositions inhibit the growth of neoplastic cells, including human breast cancer cells. Furthermore, the instant invention provides for methods of producing the compositions and methods of using the compositions to inhibit the proliferation of neoplastic cells.
Claims11
An anti-neoplastic pharmaceutical composition produced by a process comprising:
- a) providing Vernonia amygdalina leaves;
- b) soaking the leaves in water;
- c) next, gently crushing the leaves, in the water, to produce a mixture;
- d) filtering the mixture to produce a filtrate;
- e) separating the filtrate into fractions by at least one mode of chromatographic separation;
- f) identifying the fractions having antineoplastic activity;
- and,
- g) using at least one of the fractions having antineoplastic activity to produce an anti-neoplastic pharmaceutical composition.
A method of preparing an anti-neoplastic pharmaceutical composition, the method comprising the steps of:
- a) providing Vernonia amygdalina leaves;
- b) soaking the leaves in water;
- c) gently crushing the leaves, in the water, to produce a mixture;
- d) filtering the mixture to produce a filtrate;
- e) separating the filtrate in to fractions by at least one mode of chromatographic separation;
- f) identifying the fractions having antineoplastic activity;
- and,
- g) using at least one of the fractions having antineoplastic activity to produce an anti-neoplastic pharmaceutical composition.
Dependencies are inferred from the claim text.