Intraocular lens containing releasable medication

A method of preparing a hydrophilic polymer intraocular lens containing a medicated product adapted to be released after implantation in an eye, an effective quantity of a medicated product for at least partial inhibition of postoperative reactions of the eye being dispersed in the mass of the polymer, comprising the steps of:

• removing the greater part of absorbed water from a hydrophilic polymer having a given water content, immersing the hydrophilic polymer in a solution dosed with the medicated product in a medium able to impregnate the hydrophilic polymer, until the solution containing an effective quantity of a medicated product is absorbed in the polymer, conforming the hydrophilic polymer into an intraocular lens for implantation in an eye, implanting the lens, the hydrophilic polymer being sterilized before implantation and allowing the medicated product to be released progressively into the aqueous humor.

A method of preparing a hydrophilic polymer intraocular lens containing a medicated product adapted to be released after implantation in an eye, notably in substitution for a defective crystalline lens during a surgical operation, the polymer containing an effective quantity of a medicated product with appropriate effects, for at least partial inhibition of postoperative reactions of the eye being dispersed in the mass of the polymer, comprising the steps of:

• removing the greater part of absorbed water from the hydrophilic polymer having a given water content, immersing in a solution dosed with the medicated product in a medium able to impregnate the hydrophilic polymer, until the solution is substantially absorbed in the polymer, conforming the polymer into an intraocular lens for implantation in an eye, implanting the intraocular lens, and allowing the medicated product to be released progressively into the aqueous humor and/or intraocular lens and sterilizing the intraocular lens after impregnation.

A method of preparing an intraocular lens of soft material containing a medicated product releasable after implantation in an eye, the soft material being a hydrophilic polymer having a predetermined water content, and the lens being implantable in an eye, an effective quantity of a medicated product for at least partial inhibition of postoperative reactions of the eye, being dispersed in the mass of the hydrophilic polymer of the intraocular lens, the method comprising sterilizing and also immersing the intraocular lens in a solution dosed with a medicated product in a medium adapted to impregnate the hydrophilic polymer until absorption of the solution containing an effective quantity of a medicated product in the polymer of the lens.

A method of preparing an intraocular lens of soft material containing a medicated product releasable after implantation in an eye, the soft material being a polymer having a predetermined water content, and the lens being implantable in an eye, and an effective quantity of a medicated product for at least partial inhibition of postoperative reactions of the eye being dispersed in the mass of the hydrophilic polymer of the intraocular lens, the method comprising the steps of immersing the intraocular lens in a solution dosed with a medicated product in a medium adapted to impregnate the hydrophilic polymer until absorption of the solution in the polymer of the solution containing an effective quantity of a medicated product occurs in the polymer of the lens and sterilizing the lens during immersion in the solution.

A method of preparing an intraocular lens of soft material containing a medicated product releasable after implantation in an eye, the soft material being a polymer having a predetermined water content, and the lens being implantable in an eye, an effective quantity of a medicated product for at least partial inhibition of postoperative reactions of the eye being dispersed in mass of the hydrophilic polymer of the intraocular lens, the method comprising the steps of:

• sterilizing the intraocular lens and then immersing the intraocular lens in a solution dosed with a medicated product in a medium adapted to impregnate the hydrophilic polymer until absorption of the solution containing an effective quantity of a medicated product occurs in the mass of the polymer of the lens, and carrying out the immersion at ambient temperature.

An intraocular lens comprising an optic part and a haptic part, said intraocular lens being comprised of a hydrophilic polymer having a water content of at least 0.20% by weight for implantation in an eye, an effective quantity of a medicated product for at least partial inhibition of postoperative reactions of the eye being dispersed in the mass of the hydrophilic polymer of the intraocular lens, the association of the hydrophilic polymer and the dispersed medicated product being adapted to release the product progressively into the aqueous humor.

An intraocular lens comprising an optic part and a haptic part, said intraocular lens being comprised of a hydrophilic polymer having a water content of at least 0.25% by weight for implantation in an eye, an effective quantity of a medicated product for at least partial inhibition of postoperative reactions of the eye dispersed in the mass of the polymer of the intraocular lens, the association of the polymer and the dispersed medicated product being adapted to release the product progressively into the aqueous humor.