Method for producing L-amino acids by fermentation
AssigneeKyowa Hakko Kogyo Co., Ltd.
InventorsKuniki Kino, Tetsuya Abe
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Abstract
The present invention provides an industrially efficient method for producing an L-amino acid useful as medicament, chemical agent, food material and feed additive, and the method comprising culturing in a medium a microorganism having an ability to produce the L-amino acid and having resistance to a DNA gyrase inhibitor or a microorganism having an ability to produce the L-amino acid and having both resistance to a DNA gyrase inhibitor and resistance to an aminoquinoline derivative, producing and accumulating the L-amino acid therein and recovering the L-amino acid therefrom.
Claims7
A microorganism belonging to the genus Escherichia, having an ability to produce 15.7 g/l or more L-histidine and having resistance to 1 g/l novobiocin.
A microorganism belonging to the genus Escherichia, having an ability to produce and L-amino acid, and having resistance to a DNA gyrase inhibitor and to an aminoquinoline derivative, wherein the microorganism is obtained by subjecting a microorganism having an ability to produce an L-amino acid to a mutation treatment.
A microorganism belonging to the genus Escherichia, having an ability to produce L-histidine, and having resistance to a DNA gyrase inhibitor and an aminoquinoline derivative.
A microorganism selected from either Escherichia coli H-9342 (FERM BP-6675) or Escherichia coli H-9343 (FERM BP-6676).
Dependencies are inferred from the claim text.