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AssigneeThe Procter & Gamble Company
InventorsDonald Carroll Roe, Francis James Rourke, Scott Edward Osborne
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An absorbent article, at least a portion of which comprises a skin care composition that comprises an enzyme inhibitor and is at least partially transferred from the article to the skin of a wearer of the article as a result of normal contact, wearer motion and/or body heat. The enzyme inhibitor is transferred to the skin with the skin care composition and is available at the skin/urine and skin/feces interfaces to inhibit enzymatic activity on the skin and to reduce or prevent the occurrence of inflammation. Repeated application of similar treated articles to the wearer's skin provides an available source with which the enzyme inhibitor transfers onto the skin continuously over time and accumulates to provide a proactive defense against harmful enzymes for the treatment and/or prevention of diaper dermatitis.
An absorbent article having a skin care composition disposed on at least a portion of the article, the skin care composition is solid or semi-solid at 20° C. and comprises (i) from about 0.001% to about 50% of an enzyme inhibitor, (ii) from about 5% to about 95% of an emollient having a plastic or fluid consistency at 20° C., and (iii) from about 5% to about 95% of an agent capable of immobilizing the emollient in the article, wherein the immobilizing agent has a melting point of at least about 35° C. and the enzyme inhibitor has an IC50 of about 50 μM or less, as measured by a General Fecal Enzyme Method.
An absorbent article containing the skin care composition that comprises an enzyme inhibitor, wherein the enzyme inhibitor has an IC50 of about 50 μM or less, as measured by a General Fecal Enzyme Method, and the skin care composition comprising the enzyme inhibitor is at least partially transferred from the article to the skin of a wearer of the article as a result of normal contact, wearer motion, and/or body heat.
A method for reducing the enzymatic activity of a fecal enzyme on a portion of the skin of a wearer of an absorbent article, comprising the steps of (i) providing an absorbent article, at least a portion of which comprises a skin care composition that comprises an enzyme inhibitor, the enzyme inhibitor has an IC50 of about 50 μM or less, as measured by a General Fecal Enzyme Method, and (ii) transferring a portion of the skin care composition to the skin of the wearer during wear of the article.
Dependencies are inferred from the claim text.