Method for reducing or preventing transplant rejection in the eye and intraocular implants for use therefor
AssigneeOculex Pharmaceuticals, Inc.
InventorVernon G. Wong
Life of this patent
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Abstract
Methods for reducing or preventing transplant rejection in the eye of an individual are described, comprising: a) performing an ocular transplant procedure; and b) implanting in the eye a bioerodible drug delivery system comprising an immunosuppressive agent and a bioerodible polymer.
Claims45
A method for preventing transplant rejection in an eye of an individual, comprising:
- a) performing an ocular transplant procedure on an eye of an individual;
- and
- b) implanting in the eye a bioerodible drug delivery system comprising an immunosuppressive agent and a bioerodible polymer.
A method for preventing transplant rejection in the eye of an individual, comprising:
- a) performing an ocular transplant procedure on an eye of an individual;
- and
- b) implanting a solid body into the eye, wherein the body comprises particles of an immunosuppressive agent entrapped within a bioerodible polymer, and whereby the agent is released from the body by erosion of the polymer.
A kit for preventing transplant rejection in an eye, comprising:
- a) a bioerodible drug delivery system comprising an immunosuppressive agent and a bioerodible polymer, wherein the drug delivery system is designed to be implanted in an eye of an individual who has undergone or is undergoing an ocular transplant procedure;
- and
- b) instructions for use.
A method comprising
- a) performing a retinal pigment epithelium transplant or a cornea transplant on an eye of an individual;
- and
- b) placing in the eye a bioerodible drug delivery system comprising dexamethasone or cyclosporin A and a bioerodible polymer.
A method comprising placing in an eye of an individual a bioerodible drug delivery system;
- wherein the bioerodible drug delivery system includes an immunosuppressive agent and a bioerodible polymer;
- and
- wherein the eye of the individual has undergone or is undergoing an ocular transplant procedure.
Dependencies are inferred from the claim text.