HIV vaccine
AssigneeUniversity of Leeds
InventorsDavid Mark Meredith, Alexander Fred Markham
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Abstract
A herpesvirus saimiri (HVS) vector which has inserted therein at least a part of a gene encoding an envelope protein of HIV for use in delivering said protein to a specific cell population such as T cell lymphocytes and/or macrophages. The invention also provides a vaccine comprising the recombinant vector.
Claims16
A herpesvirus saimiri (HVS) vector which has inserted therein at least a part of a nucleotide sequence encoding an envelope protein of human immunodeficiency virus (HIV), wherein said HVS vector lacks or has a mutation in its STP gene (ORF1) such that the gene product is lacking or is non-functional.
A composition comprising a herpesvirus saimiri vector (HVS) which has inserted therein at least part of a nucleotide sequence encoding an envelope protein of HIV, wherein said HVS vector lacks or has a mutation in its STP gene (ORF1) such that the gene product is lacking or is non-functional.
Dependencies are inferred from the claim text.