US 6,689,166 B2Granted

Hybrid nanofibril matrices for use as tissue engineering devices

AssigneeDrexel University

InventorsCato T. Laurencin, Frank K. Ko

Life of this patent

Estimating the term…

Abstract

Tissue engineering devices with enhanced cell adhesion, cell proliferation and directional growth are provided which are prepared from nonwoven nanofibril matrices.

Claims2

Dependent claims

A tissue engineering device comprising a matrix of biocompatible nonwoven nanofibrils comprising a non-degradable polymer selected from the group consisting of polyethylenes and polyurethanes or a degradable polymer selected from the group consisting of poly(lactic acid-glycolic acid), poly(lactic acid, poly(glycolic acid), poly glaxanone), poly(orthoesters), poly(pyrolic acid) and poly(phosphazenes).

Dependencies are inferred from the claim text.

Facts

Application: 10/267,133Filed 8 Oct 2002 · continuation
Priority: 2 Apr 1998
Published: US 2003/0050711 A113 Mar 2003
Granted: 10 Feb 2004
Term ends: Not estimatedThe source records don’t support an estimate.

Classification31 codes

A61L 27/46
Having a macromolecular matrix: with phosphorus-containing inorganic fillers
A61F 2/28
Prostheses implantable into the body: bones
A61L 27/12
Inorganic materials: phosphorus-containing materials, e.g. apatite
A61L 27/58
Materials characterised by their function or physical properties , e.g. injectable or lubricating compositions, shape-memory materials, surface…:…

Family

Application60/080,445Us provisional application · filed 2 Apr 1998
PCT/US98/21369Parent of this continuation · filed 9 Oct 1998
US 2003/0050711 A1Pre-grant publication · published 13 Mar 2003
Application09/529,278Parent of this continuation
US 6,689,166 B2This patent

From the US filing history. Foreign family members aren’t listed.

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Abstract

Tissue engineering devices with enhanced cell adhesion, cell proliferation and directional growth are provided which are prepared from nonwoven nanofibril matrices.

Facts

Application

10/267,133Filed 8 Oct 2002 · continuation

Priority

2 Apr 1998

Published

US 2003/0050711 A113 Mar 2003

Granted

10 Feb 2004

Term ends

Not estimatedThe source records don’t support an estimate.

Classification31 codes

A61L 27/46
Having a macromolecular matrix: with phosphorus-containing inorganic fillers
A61F 2/28
Prostheses implantable into the body: bones
A61L 27/12
Inorganic materials: phosphorus-containing materials, e.g. apatite
A61L 27/58
Materials characterised by their function or physical properties , e.g. injectable or lubricating compositions, shape-memory materials, surface…:…

Family

Application60/080,445Us provisional application · filed 2 Apr 1998

PCT/US98/21369Parent of this continuation · filed 9 Oct 1998

US 2003/0050711 A1Pre-grant publication · published 13 Mar 2003

Application09/529,278Parent of this continuation

US 6,689,166 B2This patent

From the US filing history. Foreign family members aren’t listed.