Metal catalyzed reactions
AssigneeThe Penn State Research Foundation
InventorsXumu Zhang, Aiwen Lei
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Abstract
Compositions and processes of forming chemical bonds, such as carbon-carbon and carbon-heteroatom bonds are provided. The compositions include at least one α-halo carbonyl compound, and one or more transmetallation reagents. The transmetallation reagents are formed by the addition of a metal or metal catalyst to a target compound. The target compound is the compound undergoing chemical bond formation. Bond formation can be carried out in both intermolecular reactions (i.e. between two or more target compounds), or intramolecular (within the same target compound) reactions.
Claims19
A method of forming a chemical bond, the method comprising:
- combining at least one α-halo carbonyl compound with at least one transmetallation reagent comprising a target compound;
- and
- forming a chemical bond by substantially homocoupling the target compound.
A method of coupling a boron containing compound, the process comprising:
- combining at least one α-halo carbonyl compound with at least one catalyst and a boron compound;
- and
- substantially coupling boron containing compound with itself.
Dependencies are inferred from the claim text.