Pharmaceutical compositions having antiviral activity against human cytomegalovirus
AssigneeMurdock International Corporation
InventorsBronwyn G. Hughes, Steven G. Wood
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Abstract
The present invention is directed to the use of antiviral compounds having the following generalized structure: wherein R is 2H or ═O; R′ is OH, H, or COOH (single substitution); and R″ is OH, H, or alkyl; and pharmaceutically acceptable salts thereof as therapeutic substances having antiviral activity against human cytomegalovirus (“HCMV”) and for treating diseases caused by HCMV. Dimeric forms of the forgoing antiviral compounds having antiviral activity against HCMV are also disclosed. Pharmaceutical compositions containing the disclosed antiviral compounds are disclosed for topical and systemic administration.
Claims17
A method for treating a viral disease caused by human cytomegalovirus comprising:
- (a) obtaining a therapeutically effective dose of an antiviral compound of the formula
- wherein R is 2H or ═O;
- R′ is OH, H, or COOH (single substitution);
- and R″ is OH, H, or alkyl (single or multiple substitution);
- and pharmaceutically acceptable salts thereof, said antiviral compound having antiviral activity against a viral disease caused by human cytomegalovirus;
- and
- (b) administering the antiviral compound to a patient.
A method for treating a viral disease as defined in claim , wherein the antiviral compound is emodin anthrone.
Dependencies are inferred from the claim text.