Ultrashort-acting opioids for transdermal application
AssigneeARYx Therapeutics, Inc.
InventorPascal Druzgala
Life of this patent
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Abstract
The subject invention concerns novel analogs of fentanyl opioids. The subject invention also concerns methods for synthesizing the compounds of the invention. The invention also concerns methods for treating pain in a patient by administering a compound of the invention to a person in need of such treatment.
Claims19
An opioid compound having a structure selected from the group consisting of:
- wherein, R1 and R2 are, independently, H or CH3 and R3 is alkyl;
- wherein, R=alkyl;
- aryl;
- methoxy;
- alkyloxy;
- or aryloxy;
- wherein, R1 and R2 are, independently, H or CH3 and R3 is alkyl;
- and
- wherein, R1 and R2 are, independently, H or CH3 and R3 is alkyl.
A pharmaceutical composition comprising an opioid compound having a structure selected from the group consisting of:
- wherein, R1 and R2 are, independently, H or CH3 and R3 is alkyl;
- wherein, R=alkyl;
- aryl;
- methoxy;
- alkyloxy;
- or aryloxy;
- wherein, R1 and R2 are, independently, H or CH3 and R3 is alkyl;
- and
- wherein, R1 and R2 are, independently, H or CH3 and R3 is alkyl.
A method for treating pain wherein said method comprises administering to a patient in need of such treatment an opioid compound having
- wherein, R1 and R2 are, independently, H or CH3 and R2 is alkyl;
- wherein, R=alkyl;
- aryl;
- methoxy;
- alkyloxy;
- or aryloxy;
- wherein, R1 and R2 are, independently, H or CH3 and R3 is alkyl;
- and
- wherein, R1 and R2 are, independently, H or CH3 and R3 is alkyl.
Dependencies are inferred from the claim text.