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US 6,686,343 B1Granted
Triazolopurine derivatives, pharmaceutical compositions containing the derivatives, and adenosine A3 receptor affinitive agents
AssigneeOtsuka Pharmaceutical Factory, Inc.
InventorsTakashi Okamura, Yasuhisa Kurogi, Hiroshi Nishikawa
Life of this patent
Estimating the term…
Abstract
Disclosed is triazolopurine derivatives represented by the general formula (I): wherein R1 and R2 are as defined in the description. This compounds exhibit affinity for adenosine A3 receptor and are therefore useful as the ingredient of pharmaceutical compositions.
Claims8
A triazolopurine derivative represented by formula (1):
- wherein R1 represents a lower alkoxy lower alkyl group, a lower alkylsulfinyl lower alkyl group, a lower alkylsulfonyl lower alkyl group, a lower alkoxycarbonyl lower alkyl group, a carboxy lower alkyl group, a cycloalkyl group, a halogen-substituted lower alkyl group, a phosphono lower alkyl group, a lower alkylphosphono lower alkyl group, a di-lower alkylphosphono lower alkyl group, a lower alkanoyloxy lower alkyl group, a hydroxy lower alkyl group, a di-lower alkylamino lower alkyl group, a phenyl lower alkoxy lower alkyl group, or a lower alkylthio lower alkyl group;
- R2 represents a phenyl group which optionally has, as a substituent, 1 to 3 groups selected from the group consisting of lower alkyl group, lower alkoxy group, halogen atom, halogen-substituted lower alkyl group, and phenyl group.
Dependencies are inferred from the claim text.