Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
AssigneeApplera Corporation
InventorsEllen M. Beasley, Jane Ye, Chunhua Yan, Karen A. Ketchum, Valentina Di Francesco
Life of this patent
Estimating the term…
Abstract
The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the kinase peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the kinase peptides, and methods of identifying modulators of the kinase peptides.
Claims19
An isolated nucleic acid molecule consisting of a nucleotide sequence selected from the group consisting of:
- (a) a nucleotide sequence that encodes an amino acid sequence consisting of SEQ ID NO:2;
- (b) a nucleotide sequence consisting of SEQ ID NO:1;
- (c) a nucleotide sequence consisting of SEQ ID NO:3;
- and
- (d) a nucleotide sequence that is completely complementary to a nucleotide sequence of (a), (b), or (c).
An isolated polynucleotide consisting of the nucleotide sequence set forth in SEQ ID NO:1.
An isolated polynucleotide consisting of the nucleotide sequence set forth in SEQ ID NO:3.
An isolated nucleic acid molecule comprising a nucleotide sequence selected from the group consisting of:
- (a) a transcript/cDNA sequence that encodes an amino acid sequence consisting of SEQ ID NO:2;
- (b) SEQ ID NO:1;
- (c) nucleotides 193-1299 of SEQ ID NO:1;
- and
- (d) a nucleotide sequence that is completely complementary to a nucleotide sequence of (a), (b), or (c).
An isolated nucleic acid molecule encoding a serine/threonine kinase, wherein the nucleic acid molecule consists of a nucleotide sequence selected from the group consisting of:
- (a) a nucleotide sequence that encodes a polypeptide consisting of an amino acid sequence having at least 99% sequence identity to SEQ ID NO:2;
- (b) a nucleotide sequence having at least 99% sequence identity to SEQ ID NO:1;
- and
- (c) a nucleotide sequence having at least 99% sequence identity to SEQ ID NO:3.
An isolated polynucleotide comprising the nucleotide sequence of SEQ ID NO:1.
Dependencies are inferred from the claim text.